Effectiveness of FluMist in Adults

In healthy adults 18 to 49 years of age, FluMist demonstrated effectiveness in reducing cases of influenza1; 5; 6:

Reduction of ILI vs placebo in a multicenter, randomized, double-blind, placebo-controlled trial in 3,637 adults (FluMist n=2,411, placebo n=1,226) 18 through 49 years of age during the 7-week, site-specific outbreak period.

Effectiveness was not demonstrated in a subgroup of adults 50 years to 64 years of age.

Prevention of laboratory-documented influenza vs placebo in a multicenter, randomized, double-blind, placebo-controlled trial in 60 healthy adults (FluMist n=29, placebo n=31) 18 years to 41 years of age who were challenged with wild-type virus.

See also Efficacy in Children

Next: Safety & Tolerability